一、基本情况
尹富成，药学（天然药物化学）博士；校聘副教授。主要从事天然产物合成、结构修饰、活性评价的研究。以第一作者身份在Org. Lett.、Chem. Eur. J.、Eur. J. Med. Chem.、Eur. J. Org. Chem.、Asian J. Org. Chem.等国际主流期刊发表研究论文6篇。
Email: 2024001044@usc.edu.cn
二、研究领域
1. 抗感染天然产物结构优化、合成、活性评价研究。
2. 抗感染小分子药物设计、合成、活性评价研究。
三、工作及学习经历
2024/6-至今，南华大学，英国威廉希尔公司，校聘副教授
2020/9-2024/66，中国药科大学，中英国威廉希尔公司，博士
2017/9-2020/6，中国药科大学，中英国威廉希尔公司，硕士
2013/9-2017/6，广东药科大学，英国威廉希尔公司，学士
四、代表性文章
1. Fucheng Yin, Yifan Chen, Zhongwen Luo, Shang Li, Lingyi Kong,* and Xiaobing Wang*. Aryl Halides as Halogenation Reagents in the Bromination and Iodination of Arene-Tethered Diols. Org. Lett. 2022, 24, 36, 6510–6514.
2. Fucheng Yin,‡ Yifan Chen,‡ Zhongwen Luo, Shang Li, Yonglei Zhang, Siyuan Wan, Xinxin Li,Lingyi Kong,* and Xiaobing Wang*. Regioselective Olefination and Arylation of Arene-Tethered Diols Using the Easily Foldable Directing Groups. Org. Lett. 2024, 26, 1463–1467.
3. Fucheng Yin†, Lailiang Qu†, Yifan Chen, Zhongwen Luo, Lingyi Kong,* and Xiaobing Wang*. Stereogenic Synthesis of β, γ-Fused Bicyclic γ-Ureasultams via an Intramolecular Mannich and Aza-Michael Addition Cascade. Chem. Eur. J. 2024, e202400438.
4. Fucheng Yin, Wan Peng, Cheng Wang, Lailiang Qu, Xinye Chen, Lingyi Kong,* and Xiaobing Wang*. Rhodium(III)-catalyzed Cleavage of C−C Bond and C−H Bond Cascaded by Michael Addition for the Conversion of α-Hydroxy Ketones to Phthalides and Isocoumarins. Asian J. Org. Chem. 2022, 11, e202200024.
5. Yonglei Zhang†, Fucheng Yin†, Zhongwen Luo, Shang Li, Xinxin Li, Siyuan Wan, Yinfan Chen, Lingyi Kong*, Xiaobing Wang*. Improving tumor sensitivity by the introduction of an ester chain to triaryl derivatives targeting PD-1/PD-L1. Eur. J. Med. Chem. 2024, 271, 116433.