王佶恺

一、基本情况

王佶恺，博士，副教授，williamhill官网平台校聘教授，硕士生导师，湖南省青年骨干教师，衡阳市领军人才，中山大学访问学者。2014年毕业于中国药科大学英国威廉希尔公司，获药学学士学位，后于湖南大学（化员工物传感与计量学国家重点实验室）进行生化分析技术研究，2019年获得化学博士学位，同年在National University of Singapore进行访学交流，后入职英国威廉希尔公司。主要研究方向为基于纳米生化传感器的药物分析新方法开发，以及纳米生物成像技术的研究。主持了包括国家自然科学基金青年项目、湖南省教育厅优秀青年项目、湖南省自然科学基金青年项目等在内的多项国家和省部级课题。以第一作者/通讯作者身份在Journal of Hazardous Materials, Trends in Environmental Analytical Chemistry, Journal of Nanobiotechnology, Nano Letters, ACS Applied Materials & Interfaces，Analytical Chemistry, Journal of Pharmaceutical Analysis，Chemical Communications等期刊上发表10余篇高水平SCI论文，其中中科院一区论文10篇，并担任ACS Nano，Analytical Chemistry，Sensors and Actuators B: Chemical等SCI的审稿人。

Email: jkwang@hnu.edu.cn

二、研究领域

1.药物分析：基于功能纳米材料的药物和医学检验新方法的开发。

2.药剂学：生物医学材料合成设计与诊疗一体化探针的研究。

三、工作及学习经历

2020/3-至今，williamhill官网平台，英国威廉希尔公司，副教授（校聘教授）

2015/9-2019/10，湖南大学，化学化工学院，博士

2014/8-2015/5，湖南省药品检验研究院，药师

2010/9-2014/7，中国药科大学，英国威廉希尔公司，本科

2004/9-2010/6，衡阳市第八中学，中学

四、社会兼职

全国研究生教育评估监测专家库专家。美国化学学会会员，湖南省药学会会员。ACS Nano，Analytical Chemistry，Sensors and Actuators B: Chemical等SCI的审稿人。Interdisciplinary Medicine，Science Journal of Chemistry等杂志青年编委。

五、教学工作

承担英国威廉希尔公司课程：药物分析学、药剂学、药用高分子材料、生药学、药学前沿与进展（拔尖班）、新药研发与新药申报（研究生）。

六、承担课题

1.国家自然科学基金青年，32301161，光/炎症共激活型荧光纳米探针的设计及其原位高时空分辨成像的研究，2024/01-2026/12，主持

2.湖南省教育厅优秀青年项目，22B0455，新型硅基荧光纳米晶标记的突变敏感型SARS-COV-2核酸检测，2023/01-2025/12，主持

3.湖南省自然科学基金青年项目，2021JJ40452，基于电子俘获-近红外激励发光效应的高亮硫氧化钆纳米晶的病原体快速检测和活体诊疗研究，2021/01-2023/12，主持

4.湖南省卫生健康委科研课题，202112062218，基于超高红外转换效率镧系纳米晶的病原体便携检测和活体诊疗研究，2021/01-2023/12，主持

七、代表性文章

1. Zhu, Yanli; Wang, Jikai(Corresponding author); Pengfei Zeng;et al. Novel Ag-modified vanadate nanosheets for determination of small organic molecules with laser desorption ionization mass spectrometry,Journal ofHazardous Materials, 2023, 464(2024): 132986.

2. Zhu, Yanli; Wang, Jikai(Corresponding author); Chengxiao Fu;et al. Temporally and Spatially Resolved Molecular Profiling in Fingerprint Analysis Using Indium Vanadate Nanosheets-Assisted Laser Desorption Ionization Mass Spectrometry,Journal of Nanobiotechnology, 2023, 21, 475.

3. Zhu, Yanli; Wang, Jikai (Corresponding author); Xie, Haitao;et al. Double Signal Amplification Strategy for Dual-Analyte Fluorescent Aptasensor to Visualizing Cancer Biomarker Proteins.Analytical Chemistry, 2022, 94(29): 10451-10461.

4. Zhu, Yanli; Wang, Jikai (Corresponding author); Xie, Haitao;et al. NIR-to-Vis handheld platforms for detecting miRNA level and mutation based on sub-10 nm sulfide nanodots and HCR Amplification,ACS Applied Materials & Interfaces, 2022, 14(8): 10212-10226.

5. Zhu, Yanli; Wang, Jikai(Corresponding author); Sun, Yiyang;et al. A magneto-fluorescence bacteria assay strategy based on dual colour sulfide fluorescent nanoparticles with high near-IR conversion efficiency,Analyst, 2020, 145(13): 4436-4441.

6. Wang, Jikai(Co-corresponding author); Zeng, Pengfei; Haitao Xie;et al. An economical and flexible chip using surface-enhanced infrared absorption spectroscopy for pharmaceutical detection: combining qualitative analysis and quantitative detection,Journal of Pharmaceutical Analysis, https://doi.org/10.1016/j.jpha.2024.101076.

7. Wang, Jikai(Co-corresponding author); Xie, Zhulan; Zhu, Yanli;et al. Surface-enhanced infrared absorption spectroscopy (SEIRAS) for biochemical analysis: Progress and perspective,Trends in Environmental Analytical Chemistry, 2024, 41, e00226.

8. Wang, Jikai (Co-corresponding author); Zhu, Yanli; He, Ni;et al. Tri-doped alkaline earth sulfide nanoparticles as a new class of highly efficient probe with near-IR stimulated fluorescence for in vivo and ultrasensitive bacteria targeted imaging,Sensors and Actuators B: Chemical, 2020, 305(2020): 0-127427.

9. Wang, Jikai; Zhu, Yanli; Grimes, Craig A;et al. Multicolor lanthanide-doped CaS and SrS near-infrared stimulated luminescent nanoparticles with bright emission: application in broad-spectrum lighting, information coding, and bio-imaging,Nanoscale, 2019, 11(26): 12497-12501. (IF: 6.970 (2019))

10. Wang, Jikai; Zhu, Yanli; Grimes, Craig A;et al. Eu,Sm,Mn-Doped CaS Nanoparticles with 59.3% Upconversion-Luminescence Quantum Yield: Enabling Ultrasensitive and Facile Smartphone-Based Sulfite Detection,Analytical Chemistry, 2018, 90(14): 8658-8664. (IF: 6.350 (2018))

11. Wang, Jikai; He, Ni; Zhu, Yanli;et al. Highly-luminescent Eu,Sm,Mn-doped CaS up/down conversion nano-particles: application to ultra-sensitive latent fingerprint detection and in vivo bioimaging,Chemical Communications, 2018, 54(6): 591-594. (IF: 6.164 (2018))